Immunosuppression Induced by HIV Infection

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Immunosuppression Induced by HIV Infection

Immunosuppression due to HIV infection is a resultant of several factors including defective innate signaling pathways, increased viral replication and virus load, gradual loss of peripheral CD4+T cells and depletion of T lymphocytes at mucosal sites that collectively lead to progressive immune deficiency and AIDS development. T cells derived from HIV patients were anergic and failed to mount a...

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Stroke-induced immunosuppression and poststroke infection

Infections occur commonly after stroke and are strongly associated with an unfavourable functional outcome of these patients. Approaches for effective management of poststroke infection remain scarce, presenting an urgent need for preventive anti-infection strategies for patients who have suffered a stroke. Emerging evidence indicates that stroke impairs systemic immune responses and increases ...

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Chapter 6: Immunosuppression and co-infection with HIV.

Individuals with immunosuppression caused by HIV infection or organ transplantation are at increased risk of human papillomavirus (HPV)-associated anogenital cancers compared with age-matched healthy individuals. The exact role of immunosuppression in conferring increased risk is not known. Although it is unknown which stages of progression from dysplasia to cancer are most affected by immunosu...

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Immunosuppression by CD4+ regulatory T cells induced by chronic retroviral infection.

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ژورنال

عنوان ژورنال: Biology and Medicine

سال: 2014

ISSN: 0974-8369

DOI: 10.4172/0974-8369.1000e111